Advanced HPLC Method Development Class
A short 1.5 day course will be provided before the conference to support the HPLC 2013 Hobart Meeting.
Name of Course: ' Advanced HPLC Method Development Using Quality by Design' by Dr John Dolan (LC Resources).
Where: School of Chemistry, University of Tasmania, Hobart
When: Sunday 17th November and half a day Monday 18th November
Provided: Coffee, tea will be provided both days as well as a light lunch on Sunday.
All attendees receive an official certificate of completion after the course has finished.
Times:
Day 1 – Sunday 17th November 2013
Section 1 – Introduction to HPLC Method Development
Section 2 – HPLC Basics
Section 3 – HPLC Columns
Section 4 – Reversed-Phase Separation
Section 5 – Dealing with Ionic Samples
Section 6 – Equivalent and Orthogonal Columns
Day 2 – Monday 18th November 2013
Section 7 – Gradient Elution
Section 8 – Quality by Design
Section 9 -- Normal Phase and HILIC
Prices: Short Course Registrants Only: $1000
(Conference Attendees will receive a 10% discount on the course when they register)
To register for the course
Description of Advanced HPLC Method Development Class
The central tenant of Quality by Design (ICH Q8) is that quality cannot be tested into a product – instead it must be designed into the product. When the product is an HPLC method, QbD strategies can guide the development process to result in a standardized method development process, more easily validated methods, and methods that are easier to use and adjust in routine applications.
This 1.5- day class is designed for laboratory workers involved in HPLC method development as well as those who must transfer of existing methods into a routine laboratory. The class focuses on separation fundamentals and applies them in a time-proven strategy that applies QbD principles to developing robust HPLC methods quickly. The use of UHPLC and/or new particle technologies can enhance comprehensive method development using QbD. Based on the instructor’s extensive experience in a laboratory supporting pharmaceutical and bioanalytical methods, the attendees should gain practical skills to develop realistic HPLC methods in a short time. The techniques can be used as a stand-alone strategy or added to existing development procedures to help streamline the process. The course content assumes a basic understanding of HPLC, but not necessarily experience in method development. Students will be introduced to HPLC method development software to help find satisfactory separation conditions. Attendees will receive a comprehensive set of course notes, including copies of all visual materials presented.
Contents
Day 1
Section 1 – Introduction to HPLC Method Development
Section 2 – HPLC Basics
Section 3 – HPLC Columns
Section 4 – Reversed-Phase Separation
Section 5 – Dealing with Ionic Samples
Section 6 – Equivalent and Orthogonal Columns
Day 2
Section 7 – Gradient Elution
Section 8 – Quality by Design
Section 9 -- Normal Phase and HILIC
This course makes use of chromatography simulation software as a teaching tool to help reinforce the principles discussed during the lectures. The principles used in computer modeling are fully applicable to separations in your lab. You will learn how to do the best possible chromatography. Save hours of frustration and improve your results time after time.
Our main goal is not to get through a canned curriculum, but to provide practical help to attendees that can be applied in real situations in the lab. Students are encouraged to bring questions, separations problems, and other topics of interest to discuss during the class or one-on-one with the instructor.